Cannabidiol for neuroprotection in hypoxic-ischemic encephalopathy
Cannabidiol, administered at 1mg/kg up to 18 h after hypoxia ischemia prevents the resulting brain damage, protecting neurons and astrocytes, protecting myelinization , restoring brain activity and function and preventing behavioural consequences. Cannabinoid CB2 receptors are somehow involved in these effects. Serotonin 5HT1A receptors are involved in the cannabidiol histological, biochemical and motor protective effects and mediate the behavioural effects of cannabidiol.
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Produktinformationen "Cannabidiol for neuroprotection in hypoxic-ischemic encephalopathy"
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Mohammed El Demerdash, Nagat
NAGAT MOHAMMED EL DEMERDASH, MD; PhD Madrid, Spain. Nationality: Egyptian; Education: International Ph.D. Medicine; Autonomous University of Madrid, Spain, 2014 Thesis: "Cannabidiol for Neuroprotection in Newborn Hypoxic-Ischemic Encephalopathy: pharmacological aspects and mechanisms of action".
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